The wet sand has less trash, but it may be barren of targets. Here in NJ, the wet sand has been brutal due to hardly any targets or storms to pull/move some of the sand out to expose the deeper targets. Lots of guys have now taken up hunting in the dry sand because there are targets there. Lots more trash ( and 'bad' trash in the form of pull tabs and foil, which has to be dug of you will miss most gold jewelry).
So....I say start in the wet sand and move in a big S type/zig zag pattern walking parallel to the water, going from the water line to the semi-wet sand. If you start to hit targets, check out the line where the targets are being found. Then start a smaller S pattern on that line. If you hit any deep green quarters, nickels or sinkers, start to grid that area slowly and from different angels. Hitting deep sinkers and quarters means your detector is hitting the deeper, denser targets and will be able to possibly hit a nice gold target.
If you are walking into the wet sand and sinking in 3-4 inches, or pulling out deep pull tabs, get outta there and find a spot in the wet sand with compact sand and where you are at least getting coins.
If there aren't many targets in the wet sand, then move up into the dry.
Not sure what unit you will be using, but the number one rule for wet sand hunting, especially in salt water, is the run with a stable unit until you get to know the conditions. Starting out with too much sensitivity or running at the edge where the unit becomes unstable is a recipe for disaster if you don't know your unit's ability in the conditions.
Lastly...if there isn't much trash in the wet sand, run in all metal and dig everything at first to get an idea what is down there.