Overall comfort of any detector is something I have long considered. I have a bad back, shoulder and neck. I can use the 'S' rod models without much of a problem, but I can also notice some differences in feel and fit after an ample time afield.
For me, it was an easy selection because I had been using the Teknetics Omega. The Omega uses the stand-up T2 grip, which I had also liked, but the Omega has a smaller housing and no battery system like the T2. After using the Omega along with a Delta an Gamma, I found none of them to cause a 'problem,' but I also found that I preferred the Omega's grip shape and the balance of the whole unit.
The G2 uses the same rod and grip system, so it was an easy pick. I worked the G2 and Gold Bug Pro side-by-side in several field evaluations, and the only difference between them is the rod & grip set-up. A friend I hunt with prefers the standard 'S' rod to the G2/Omega grip design, and he told me he thought it was more comfortable for him. I guess we just have to pick what seems to feel best and fit the best for our own pleasure of hunting.
Monte